{"id":2602,"date":"2024-11-26T02:07:47","date_gmt":"2024-11-25T22:37:47","guid":{"rendered":"http:\/\/uro-med.ir\/kidney-cancer\/?page_id=2602"},"modified":"2025-05-16T09:51:22","modified_gmt":"2025-05-16T06:21:22","slug":"advance-and-metastatic-rcc","status":"publish","type":"page","link":"https:\/\/uro-med.ir\/kidney-cancer\/advance-and-metastatic-rcc\/","title":{"rendered":"advance and metastatic Rcc"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"2602\" class=\"elementor elementor-2602\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-41ddc08 e-con-full e-flex e-con e-parent\" data-id=\"41ddc08\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-642e88d elementor-widget elementor-widget-spacer\" data-id=\"642e88d\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div 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\\u0646\\u0645\\u06cc\\u200c\\u062a\\u0648\\u0627\\u0646\\u0646\\u062f \\u062f\\u0631\\u0645\\u0627\\u0646 \\u0645\\u0628\\u062a\\u0646\\u06cc \\u0628\\u0631 PD-1 \\u062f\\u0631\\u06cc\\u0627\\u0641\\u062a \\u06a9\\u0646\\u0646\\u062f\\u060c \\u06af\\u0632\\u06cc\\u0646\\u0647\\u200c\\u0627\\u06cc \\u0645\\u0646\\u0627\\u0633\\u0628 \\u0645\\u062d\\u0633\\u0648\\u0628 \\u0645\\u06cc\\u200c\\u0634\\u0648\\u062f \\u200f(II, A).&lt;\\\/li&gt;\\n&lt;li&gt;\\u062a\\u0631\\u06a9\\u06cc\\u0628&lt;strong&gt;Axitinib\\u2013avelumab&lt;\\\/strong&gt; \\u0645\\u0632\\u06cc\\u062a\\u06cc \\u062f\\u0631 \\u0628\\u0642\\u0627\\u06cc \\u06a9\\u0644\\u06cc (OS) \\u0646\\u0633\\u0628\\u062a \\u0628\\u0647 Sunitinib \\u0646\\u0634\\u0627\\u0646 \\u0646\\u062f\\u0627\\u062f\\u0647 \\u0627\\u0633\\u062a \\u0648 \\u0628\\u0646\\u0627\\u0628\\u0631\\u0627\\u06cc\\u0646 &lt;strong&gt;\\u0646\\u0633\\u0628\\u062a \\u0628\\u0647 \\u062f\\u0631\\u0645\\u0627\\u0646 \\u0628\\u0627 &lt;\\\/strong&gt;&lt;strong&gt;TKI&lt;\\\/strong&gt;&lt;strong&gt; \\u062a\\u06a9\\u200c\\u062f\\u0627\\u0631\\u0648\\u06cc\\u06cc \\u0628\\u0631\\u062a\\u0631\\u06cc \\u0646\\u062f\\u0627\\u0631\\u062f \\u0648 \\u062a\\u0648\\u0635\\u06cc\\u0647 \\u0646\\u0645\\u06cc\\u200c\\u0634\\u0648\\u062f&lt;\\\/strong&gt; \\u200f[I, D\\u061b \\u0627\\u0645\\u062a\\u06cc\\u0627\\u0632 ESMO-MCBS : \\u06f3].&lt;\\\/li&gt;\\n&lt;li&gt;&lt;strong&gt;\\u067e\\u0627\\u06cc\\u0634 \\u0641\\u0639\\u0627\\u0644 (&lt;\\\/strong&gt;&lt;strong&gt;surveillance&lt;\\\/strong&gt;&lt;strong&gt;)&lt;\\\/strong&gt; \\u0645\\u06cc\\u200c\\u062a\\u0648\\u0627\\u0646\\u062f \\u062f\\u0631 &lt;strong&gt;\\u062a\\u062d\\u062a\\u200c\\u0645\\u062c\\u0645\\u0648\\u0639\\u0647\\u200c\\u06cc \\u06a9\\u0648\\u0686\\u06a9\\u06cc \\u0627\\u0632 \\u0628\\u06cc\\u0645\\u0627\\u0631\\u0627\\u0646 \\u0628\\u0627 \\u0631\\u06cc\\u0633\\u06a9 \\u0645\\u0637\\u0644\\u0648\\u0628&lt;\\\/strong&gt; \\u06a9\\u0647 \\u062f\\u0642\\u06cc\\u0642\\u0627\\u064b \\u062a\\u0639\\u0631\\u06cc\\u0641 \\u0646\\u0634\\u062f\\u0647\\u200c\\u0627\\u0646\\u062f\\u060c \\u06af\\u0632\\u06cc\\u0646\\u0647\\u200c\\u06cc \\u062c\\u0627\\u06cc\\u06af\\u0632\\u06cc\\u0646 \\u0628\\u0627\\u0634\\u062f (III, C). \\u0627\\u06cc\\u0646 \\u0631\\u0648\\u06cc\\u06a9\\u0631\\u062f \\u0646\\u06cc\\u0627\\u0632\\u0645\\u0646\\u062f \\u0628\\u0631\\u0631\\u0633\\u06cc \\u0648 \\u0645\\u0644\\u0627\\u062d\\u0638\\u0627\\u062a \\u062f\\u0642\\u06cc\\u0642 \\u0628\\u0627\\u0644\\u06cc\\u0646\\u06cc \\u0627\\u0633\\u062a.&lt;\\\/li&gt;\\n&lt;li&gt;&lt;strong&gt;\\u0642\\u0637\\u0639 \\u062f\\u0631\\u0645\\u0627\\u0646 \\u0628\\u0627 \\u0645\\u0647\\u0627\\u0631\\u06a9\\u0646\\u0646\\u062f\\u0647\\u200c\\u0647\\u0627\\u06cc \\u0627\\u06cc\\u0645\\u0646\\u06cc (&lt;\\\/strong&gt;&lt;strong&gt;ICIs&lt;\\\/strong&gt;&lt;strong&gt;)&lt;\\\/strong&gt; \\u067e\\u0633 \\u0627\\u0632 &lt;strong&gt;\\u06f2 \\u0633\\u0627\\u0644 \\u062f\\u0631\\u0645\\u0627\\u0646&lt;\\\/strong&gt; \\u0628\\u0627\\u06cc\\u062f \\u0645\\u0648\\u0631\\u062f \\u062a\\u0648\\u062c\\u0647 \\u0642\\u0631\\u0627\\u0631 \\u06af\\u06cc\\u0631\\u062f (IV, B).&lt;\\\/li&gt;\\n&lt;li&gt;&lt;strong&gt;\\u0648\\u0642\\u0641\\u0647\\u200c\\u0647\\u0627\\u06cc \\u062f\\u0631\\u0645\\u0627\\u0646\\u06cc \\u062f\\u0631 \\u0645\\u0635\\u0631\\u0641 &lt;\\\/strong&gt;&lt;strong&gt;TKI&lt;\\\/strong&gt;&lt;strong&gt;\\u0647\\u0627\\u06cc \\u0636\\u062f &lt;\\\/strong&gt;&lt;strong&gt;VEGFR&lt;\\\/strong&gt; \\u0628\\u0647 \\u0646\\u0638\\u0631 \\u0646\\u0645\\u06cc\\u200c\\u0631\\u0633\\u062f \\u0627\\u062b\\u0631 \\u0645\\u0646\\u0641\\u06cc \\u0628\\u0631 \\u0627\\u062b\\u0631\\u0628\\u062e\\u0634\\u06cc \\u06a9\\u0644\\u06cc \\u062f\\u0631\\u0645\\u0627\\u0646 \\u062f\\u0627\\u0634\\u062a\\u0647 \\u0628\\u0627\\u0634\\u062f (I, C).&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;&quot;,&quot;hotspot_offset_x&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:12,&quot;sizes&quot;:[]},&quot;hotspot_offset_y&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:71,&quot;sizes&quot;:[]},&quot;hotspot_tooltip_position&quot;:&quot;yes&quot;,&quot;hotspot_position&quot;:&quot;right&quot;,&quot;hotspot_tooltip_width&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:409,&quot;sizes&quot;:[]},&quot;hotspot_tooltip_text_wrap&quot;:&quot;yes&quot;,&quot;_id&quot;:&quot;402af98&quot;,&quot;hotspot_label&quot;:&quot;&quot;,&quot;hotspot_link&quot;:{&quot;url&quot;:&quot;&quot;,&quot;is_external&quot;:&quot;&quot;,&quot;nofollow&quot;:&quot;&quot;,&quot;custom_attributes&quot;:&quot;&quot;},&quot;hotspot_horizontal&quot;:&quot;right&quot;,&quot;hotspot_vertical&quot;:&quot;top&quot;},{&quot;hotspot_icon&quot;:{&quot;value&quot;:&quot;fas fa-info-circle&quot;,&quot;library&quot;:&quot;fa-solid&quot;},&quot;hotspot_custom_size&quot;:&quot;&quot;,&quot;hotspot_tooltip_content&quot;:&quot;&lt;ul&gt;\\n&lt;li&gt;\\u0627\\u062f\\u0627\\u0645\\u0647 \\u062f\\u0631\\u0645\\u0627\\u0646 \\u0628\\u0627 &lt;strong&gt;\\u0645\\u0647\\u0627\\u0631\\u06a9\\u0646\\u0646\\u062f\\u0647\\u200c\\u0647\\u0627\\u06cc&lt;\\\/strong&gt;&lt;strong&gt; VEGFR TKI &lt;\\\/strong&gt;&lt;strong&gt;\\u067e\\u0633 \\u0627\\u0632 \\u062f\\u0631\\u0645\\u0627\\u0646 \\u062e\\u0637 \\u0627\\u0648\\u0644 \\u0628\\u0627 \\u062a\\u0631\\u06a9\\u06cc\\u0628\\u0627\\u062a \\u0647\\u062f\\u0641\\u0645\\u0646\\u062f \\u0639\\u0644\\u06cc\\u0647&lt;\\\/strong&gt; &lt;strong&gt;PD-1&lt;\\\/strong&gt;\\u060c \\u0627\\u0633\\u062a\\u0627\\u0646\\u062f\\u0627\\u0631\\u062f \\u0645\\u0631\\u0627\\u0642\\u0628\\u062a\\u06cc \\u0645\\u062d\\u0633\\u0648\\u0628 \\u0645\\u06cc\\u200c\\u0634\\u0648\\u062f \\u200f[I, B].&lt;\\\/li&gt;\\n&lt;li&gt;\\u0628\\u0627\\u06cc\\u062f \\u0627\\u0632 &lt;strong&gt;\\u062f\\u0627\\u0631\\u0648\\u0647\\u0627\\u06cc \\u0636\\u062f&lt;\\\/strong&gt;&lt;strong&gt; VEGFR&lt;\\\/strong&gt; \\u06a9\\u0647 \\u0642\\u0628\\u0644\\u0627\\u064b \\u0627\\u0633\\u062a\\u0641\\u0627\\u062f\\u0647 \\u0646\\u0634\\u062f\\u0647\\u200c\\u0627\\u0646\\u062f \\u0628\\u0647\\u0631\\u0647 \\u06af\\u0631\\u0641\\u062a \\u200f[I, B].&lt;\\\/li&gt;\\n&lt;li&gt;&lt;strong&gt;Cabozantinib&lt;\\\/strong&gt; \\u062f\\u0627\\u0631\\u0648\\u06cc \\u0627\\u0631\\u062c\\u062d \\u0628\\u0631\\u0627\\u06cc \\u062f\\u0631\\u0645\\u0627\\u0646 \\u062e\\u0637 \\u062f\\u0648\\u0645 \\u0627\\u0633\\u062a \\u200f[II, B].&lt;\\\/li&gt;\\n&lt;li&gt;\\u0633\\u0627\\u06cc\\u0631 \\u06af\\u0632\\u06cc\\u0646\\u0647\\u200c\\u0647\\u0627 \\u0646\\u06cc\\u0632 \\u0634\\u0627\\u0645\\u0644 &lt;strong&gt;Axitinib&lt;\\\/strong&gt;\\u060c &lt;strong&gt;Lenvatinib\\u2013Everolimus&lt;\\\/strong&gt;\\u060c &lt;strong&gt;Pazopanib&lt;\\\/strong&gt;\\u060c &lt;strong&gt;Sunitinib&lt;\\\/strong&gt; \\u0648 &lt;strong&gt;Tivozanib&lt;\\\/strong&gt; \\u0647\\u0633\\u062a\\u0646\\u062f \\u200f[III, B].&lt;\\\/li&gt;\\n&lt;li&gt;\\u062f\\u0631 \\u0628\\u06cc\\u0645\\u0627\\u0631\\u0627\\u0646\\u06cc \\u06a9\\u0647 \\u062f\\u0631 \\u062e\\u0637 \\u0627\\u0648\\u0644 &lt;strong&gt;\\u062f\\u0631\\u0645\\u0627\\u0646 \\u0628\\u0627&lt;\\\/strong&gt;&lt;strong&gt; TKI &lt;\\\/strong&gt;&lt;strong&gt;\\u0636\\u062f&lt;\\\/strong&gt;&lt;strong&gt; VEGFR&lt;\\\/strong&gt; \\u062f\\u0631\\u06cc\\u0627\\u0641\\u062a \\u06a9\\u0631\\u062f\\u0647\\u200c\\u0627\\u0646\\u062f:&lt;\\\/li&gt;\\n&lt;li&gt;&lt;strong&gt;Nivolumab&lt;\\\/strong&gt; (\\u062f\\u0631 \\u0635\\u0648\\u0631\\u062a \\u062f\\u0631 \\u062f\\u0633\\u062a\\u0631\\u0633 \\u0628\\u0648\\u062f\\u0646 \\u0648 \\u0646\\u0628\\u0648\\u062f \\u06a9\\u0646\\u062a\\u0631\\u0627\\u0627\\u0646\\u062f\\u06cc\\u06a9\\u0627\\u0633\\u06cc\\u0648\\u0646) \\u200f(I, A\\u061b \\u0627\\u0645\\u062a\\u06cc\\u0627\\u0632 ESMO-MCBS : \\u06f5) \\u0648 &lt;strong&gt;Cabozantinib&lt;\\\/strong&gt; \\u200f[I, A] \\u00a0\\u0647\\u0631 \\u062f\\u0648 \\u0628\\u0627\\u0639\\u062b &lt;strong&gt;\\u0627\\u0641\\u0632\\u0627\\u06cc\\u0634 \\u0628\\u0642\\u0627\\u06cc \\u06a9\\u0644\\u06cc&lt;\\\/strong&gt;&lt;strong&gt; (OS)&lt;\\\/strong&gt; \\u0645\\u06cc\\u200c\\u0634\\u0648\\u0646\\u062f.&lt;\\\/li&gt;\\n&lt;li&gt;\\u0633\\u0627\\u06cc\\u0631 \\u06af\\u0632\\u06cc\\u0646\\u0647\\u200c\\u0647\\u0627\\u06cc \\u0642\\u0627\\u0628\\u0644\\u200c\\u0627\\u0633\\u062a\\u0641\\u0627\\u062f\\u0647 \\u0639\\u0628\\u0627\\u0631\\u062a\\u200c\\u0627\\u0646\\u062f \\u0627\\u0632: &lt;strong&gt;Axitinib&lt;\\\/strong&gt;\\u060c &lt;strong&gt;Everolimus&lt;\\\/strong&gt; \\u0648 &lt;strong&gt;Lenvatinib\\u2013Everolimus&lt;\\\/strong&gt; \\u200f[II, B].&lt;\\\/li&gt;\\n&lt;li&gt;&lt;strong&gt;Belzutifan&lt;\\\/strong&gt; \\u0646\\u06cc\\u0632 \\u06af\\u0632\\u06cc\\u0646\\u0647\\u200c\\u06cc \\u062c\\u0627\\u06cc\\u06af\\u0632\\u06cc\\u0646 \\u0628\\u0631\\u0627\\u06cc \\u0628\\u06cc\\u0645\\u0627\\u0631\\u0627\\u0646\\u06cc \\u0627\\u0633\\u062a \\u06a9\\u0647 \\u067e\\u0633 \\u0627\\u0632 \\u062f\\u0631\\u06cc\\u0627\\u0641\\u062a &lt;strong&gt;\\u062f\\u0631\\u0645\\u0627\\u0646 \\u062a\\u0631\\u06a9\\u06cc\\u0628\\u06cc \\u0636\\u062f&lt;\\\/strong&gt;&lt;strong&gt; VEGFR\\u2013PD-1&lt;\\\/strong&gt; \\u00a0\\u062f\\u0686\\u0627\\u0631 \\u067e\\u06cc\\u0634\\u0631\\u0641\\u062a \\u0628\\u06cc\\u0645\\u0627\\u0631\\u06cc \\u0634\\u062f\\u0647\\u200c\\u0627\\u0646\\u062f \\u200f(III, B\\u061b \\u062f\\u0627\\u0631\\u0627\\u06cc \\u062a\\u0623\\u06cc\\u06cc\\u062f\\u06cc\\u0647 FDA \\u0648\\u0644\\u06cc \\u0641\\u0627\\u0642\\u062f \\u062a\\u0623\\u06cc\\u06cc\\u062f\\u06cc\\u0647 EMA).&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;&quot;,&quot;hotspot_offset_x&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:12,&quot;sizes&quot;:[]},&quot;hotspot_offset_y&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:95,&quot;sizes&quot;:[]},&quot;hotspot_tooltip_position&quot;:&quot;yes&quot;,&quot;hotspot_position&quot;:&quot;bottom&quot;,&quot;hotspot_tooltip_width&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:409,&quot;sizes&quot;:[]},&quot;hotspot_tooltip_text_wrap&quot;:&quot;yes&quot;,&quot;_id&quot;:&quot;d44ae3f&quot;,&quot;hotspot_label&quot;:&quot;&quot;,&quot;hotspot_link&quot;:{&quot;url&quot;:&quot;&quot;,&quot;is_external&quot;:&quot;&quot;,&quot;nofollow&quot;:&quot;&quot;,&quot;custom_attributes&quot;:&quot;&quot;},&quot;hotspot_horizontal&quot;:&quot;right&quot;,&quot;hotspot_vertical&quot;:&quot;top&quot;}],&quot;tooltip_position&quot;:&quot;right&quot;,&quot;hotspot_sequenced_animation&quot;:&quot;no&quot;,&quot;tooltip_trigger&quot;:&quot;click&quot;,&quot;tooltip_animation&quot;:&quot;e-hotspot--fade-in-out&quot;}\" data-widget_type=\"hotspot.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"689\" src=\"https:\/\/uro-med.ir\/kidney-cancer\/wp-content\/uploads\/2025\/05\/advance-and-metastatic-rcc.jpg\" class=\"attachment-large size-large wp-image-4328\" alt=\"\" srcset=\"https:\/\/uro-med.ir\/kidney-cancer\/wp-content\/uploads\/2025\/05\/advance-and-metastatic-rcc.jpg 835w, https:\/\/uro-med.ir\/kidney-cancer\/wp-content\/uploads\/2025\/05\/advance-and-metastatic-rcc-500x431.jpg 500w, https:\/\/uro-med.ir\/kidney-cancer\/wp-content\/uploads\/2025\/05\/advance-and-metastatic-rcc-300x258.jpg 300w, https:\/\/uro-med.ir\/kidney-cancer\/wp-content\/uploads\/2025\/05\/advance-and-metastatic-rcc-768x661.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-6490865  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<ol>\n<li>\u062a\u0631\u06a9\u06cc\u0628 <strong>Lenvatinib\u2013pembrolizumab<\/strong> \u200f(I, A\u061b \u0627\u0645\u062a\u06cc\u0627\u0632 ESMO-MCBS: \u06f4)\u060c <strong>Axitinib\u2013pembrolizumab<\/strong> \u00a0\u200f(I, A\u061b \u0627\u0645\u062a\u06cc\u0627\u0632: \u06f4) \u06cc\u0627 <strong>Cabozantinib\u2013nivolumab<\/strong> \u200f (I, A\u061b \u0627\u0645\u062a\u06cc\u0627\u0632: \u06f1) \u0628\u0631\u0627\u06cc \u062f\u0631\u0645\u0627\u0646 \u062e\u0637 \u0627\u0648\u0644 ccRCC \u067e\u06cc\u0634\u0631\u0641\u062a\u0647 \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c <strong>\u0635\u0631\u0641\u200c\u0646\u0638\u0631 \u0627\u0632 \u06af\u0631\u0648\u0647 \u062e\u0637\u0631 \u062f\u0631 \u0637\u0628\u0642\u0647\u200c\u0628\u0646\u062f\u06cc <\/strong><strong>IMDC<\/strong>.<\/li>\n<li><strong>\u0647\u06cc\u0686 \u062a\u0631\u06a9\u06cc\u0628 \u062a\u0631\u062c\u06cc\u062d\u06cc<\/strong> \u0645\u06cc\u0627\u0646 \u0645\u0647\u0627\u0631\u06a9\u0646\u0646\u062f\u0647 PD-1 \u0648 TKI\u0647\u0627\u06cc \u0636\u062f VEGFR \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0631\u062f \u0648 <strong>\u0645\u0642\u0627\u06cc\u0633\u0647\u200c\u0647\u0627\u06cc \u063a\u06cc\u0631\u0645\u0633\u062a\u0642\u06cc\u0645 \u0645\u06cc\u0627\u0646 \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u0645\u062e\u062a\u0644\u0641 \u062a\u0648\u0635\u06cc\u0647 \u0646\u0645\u06cc\u200c\u0634\u0648\u062f<\/strong>.<\/li>\n<li>\u062a\u0631\u06a9\u06cc\u0628 <strong>Ipilimumab\u2013nivolumab<\/strong> \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 <strong>\u0631\u06cc\u0633\u06a9 \u0645\u062a\u0648\u0633\u0637 \u06cc\u0627 \u0628\u0627\u0644\u0627 \u0628\u0631 \u0627\u0633\u0627\u0633 <\/strong><strong>IMDC<\/strong> \u00a0\u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f (I, A\u061b \u0627\u0645\u062a\u06cc\u0627\u0632 ESMO-MCBS:4) \u0648 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u0628\u0647\u200c\u0639\u0646\u0648\u0627\u0646 \u06cc\u06a9 <strong>\u06af\u0632\u06cc\u0646\u0647 \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 \u0631\u06cc\u0633\u06a9 \u0645\u0637\u0644\u0648\u0628 (<\/strong><strong>favourable-risk<\/strong><strong>)<\/strong> \u0646\u06cc\u0632 \u0645\u0637\u0631\u062d \u0634\u0648\u062f \u200f(I, C).<\/li>\n<li>\u062a\u0631\u06a9\u06cc\u0628 <strong>Axitinib\u2013toripalimab<\/strong> \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 <strong>\u0631\u06cc\u0633\u06a9 \u0645\u062a\u0648\u0633\u0637 \u06cc\u0627 \u0628\u0627\u0644\u0627<\/strong> \u0628\u0647\u200c\u06a9\u0627\u0631 \u0631\u0648\u062f \u200f(I, C)\u061b \u0628\u0627 \u0627\u06cc\u0646 \u062d\u0627\u0644\u060c \u0627\u06cc\u0646 \u062a\u0631\u06a9\u06cc\u0628 <strong>\u0647\u0646\u0648\u0632 \u062a\u0623\u06cc\u06cc\u062f\u06cc\u0647 <\/strong><strong>FDA<\/strong> <strong>\u00a0<\/strong><strong>\u06cc\u0627 <\/strong><strong>EMA<\/strong> <strong>\u00a0<\/strong><strong>\u0631\u0627 \u062f\u0631\u06cc\u0627\u0641\u062a \u0646\u06a9\u0631\u062f\u0647 \u0627\u0633\u062a<\/strong>.<\/li>\n<li>\u062f\u0627\u0631\u0648\u0647\u0627\u06cc <strong>Sunitinib<\/strong> \u200f[I, C]\u060c <strong>Pazopanib<\/strong> \u200f [I, C] \u00a0\u0648 <strong>Tivozanib<\/strong> \u200f[II, C] \u00a0\u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u0646\u062f \u0628\u0647\u200c\u0639\u0646\u0648\u0627\u0646 <strong>\u062c\u0627\u06cc\u06af\u0632\u06cc\u0646\u200c\u0647\u0627\u06cc \u0628\u0627\u0644\u0642\u0648\u0647<\/strong> \u0628\u0631\u0627\u06cc \u062a\u0631\u06a9\u06cc\u0628\u0627\u062a \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 PD-1 \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 <strong>\u0631\u06cc\u0633\u06a9 \u0645\u0637\u0644\u0648\u0628 \u0628\u0631 \u0627\u0633\u0627\u0633 <\/strong><strong>IMDC<\/strong> \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0634\u0648\u0646\u062f\u060c \u0632\u06cc\u0631\u0627 <strong>\u0634\u0648\u0627\u0647\u062f \u0631\u0648\u0634\u0646\u06cc \u0627\u0632 \u0628\u0631\u062a\u0631\u06cc \u062a\u0631\u06a9\u06cc\u0628\u0627\u062a <\/strong><strong>PD-1 <\/strong><strong>\u0646\u0633\u0628\u062a \u0628\u0647 <\/strong><strong>Sunitinib<\/strong><strong> \u062f\u0631 \u0627\u06cc\u0646 \u06af\u0631\u0648\u0647 \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0631\u062f<\/strong>.<\/li>\n<li>\u00a0<\/li>\n<\/ol>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-402af98  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<p>\u00a0<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li>\u062f\u0627\u0631\u0648\u0647\u0627\u06cc <strong>Sunitinib<\/strong> \u200f[I, A]\u060c <strong>Pazopanib<\/strong> \u00a0\u200f[I, A] \u00a0\u0648<strong>Tivozanib<\/strong> \u200f[II, B] \u0628\u0647\u200c\u0639\u0646\u0648\u0627\u0646 \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646\u200c\u0647\u0627\u06cc \u062a\u0631\u06a9\u06cc\u0628\u0627\u062a \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0645\u0647\u0627\u0631\u06a9\u0646\u0646\u062f\u0647\u200c\u0647\u0627\u06cc PD-1 \u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u062e\u0637 \u0627\u0648\u0644 \u0645\u0637\u0631\u062d \u0647\u0633\u062a\u0646\u062f\u060c \u0628\u0647\u200c\u0648\u06cc\u0698\u0647 \u0632\u0645\u0627\u0646\u06cc \u06a9\u0647 \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 ICI\u0647\u0627 <strong>\u06a9\u0646\u062a\u0631\u0627\u0627\u0646\u062f\u06cc\u06a9\u0627\u0633\u06cc\u0648\u0646 \u062f\u0627\u0631\u062f \u06cc\u0627 \u062f\u0631 \u062f\u0633\u062a\u0631\u0633 \u0646\u06cc\u0633\u062a<\/strong>.<\/li>\n<li>\u062f\u0627\u0631\u0648\u06cc <strong>Cabozantinib<\/strong> \u0646\u06cc\u0632 \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 <strong>\u0631\u06cc\u0633\u06a9 \u0645\u062a\u0648\u0633\u0637 \u06cc\u0627 \u0628\u0627\u0644\u0627 \u0628\u0631 \u0627\u0633\u0627\u0633 \u0637\u0628\u0642\u0647\u200c\u0628\u0646\u062f\u06cc<\/strong><strong>IMDC<\/strong> \u06a9\u0647 \u0646\u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u0646\u062f \u062f\u0631\u0645\u0627\u0646 \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 PD-1 \u062f\u0631\u06cc\u0627\u0641\u062a \u06a9\u0646\u0646\u062f\u060c \u06af\u0632\u06cc\u0646\u0647\u200c\u0627\u06cc \u0645\u0646\u0627\u0633\u0628 \u0645\u062d\u0633\u0648\u0628 \u0645\u06cc\u200c\u0634\u0648\u062f \u200f(II, A).<\/li>\n<li>\u062a\u0631\u06a9\u06cc\u0628<strong>Axitinib\u2013avelumab<\/strong> \u0645\u0632\u06cc\u062a\u06cc \u062f\u0631 \u0628\u0642\u0627\u06cc \u06a9\u0644\u06cc (OS) \u0646\u0633\u0628\u062a \u0628\u0647 Sunitinib \u0646\u0634\u0627\u0646 \u0646\u062f\u0627\u062f\u0647 \u0627\u0633\u062a \u0648 \u0628\u0646\u0627\u0628\u0631\u0627\u06cc\u0646 <strong>\u0646\u0633\u0628\u062a \u0628\u0647 \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 <\/strong><strong>TKI<\/strong><strong> \u062a\u06a9\u200c\u062f\u0627\u0631\u0648\u06cc\u06cc \u0628\u0631\u062a\u0631\u06cc \u0646\u062f\u0627\u0631\u062f \u0648 \u062a\u0648\u0635\u06cc\u0647 \u0646\u0645\u06cc\u200c\u0634\u0648\u062f<\/strong> \u200f[I, D\u061b \u0627\u0645\u062a\u06cc\u0627\u0632 ESMO-MCBS : \u06f3].<\/li>\n<li><strong>\u067e\u0627\u06cc\u0634 \u0641\u0639\u0627\u0644 (<\/strong><strong>surveillance<\/strong><strong>)<\/strong> \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u062f\u0631 <strong>\u062a\u062d\u062a\u200c\u0645\u062c\u0645\u0648\u0639\u0647\u200c\u06cc \u06a9\u0648\u0686\u06a9\u06cc \u0627\u0632 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 \u0631\u06cc\u0633\u06a9 \u0645\u0637\u0644\u0648\u0628<\/strong> \u06a9\u0647 \u062f\u0642\u06cc\u0642\u0627\u064b \u062a\u0639\u0631\u06cc\u0641 \u0646\u0634\u062f\u0647\u200c\u0627\u0646\u062f\u060c \u06af\u0632\u06cc\u0646\u0647\u200c\u06cc \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646 \u0628\u0627\u0634\u062f (III, C). \u0627\u06cc\u0646 \u0631\u0648\u06cc\u06a9\u0631\u062f \u0646\u06cc\u0627\u0632\u0645\u0646\u062f \u0628\u0631\u0631\u0633\u06cc \u0648 \u0645\u0644\u0627\u062d\u0638\u0627\u062a \u062f\u0642\u06cc\u0642 \u0628\u0627\u0644\u06cc\u0646\u06cc \u0627\u0633\u062a.<\/li>\n<li><strong>\u0642\u0637\u0639 \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 \u0645\u0647\u0627\u0631\u06a9\u0646\u0646\u062f\u0647\u200c\u0647\u0627\u06cc \u0627\u06cc\u0645\u0646\u06cc (<\/strong><strong>ICIs<\/strong><strong>)<\/strong> \u067e\u0633 \u0627\u0632 <strong>\u06f2 \u0633\u0627\u0644 \u062f\u0631\u0645\u0627\u0646<\/strong> \u0628\u0627\u06cc\u062f \u0645\u0648\u0631\u062f \u062a\u0648\u062c\u0647 \u0642\u0631\u0627\u0631 \u06af\u06cc\u0631\u062f (IV, B).<\/li>\n<li><strong>\u0648\u0642\u0641\u0647\u200c\u0647\u0627\u06cc \u062f\u0631\u0645\u0627\u0646\u06cc \u062f\u0631 \u0645\u0635\u0631\u0641 <\/strong><strong>TKI<\/strong><strong>\u0647\u0627\u06cc \u0636\u062f <\/strong><strong>VEGFR<\/strong> \u0628\u0647 \u0646\u0638\u0631 \u0646\u0645\u06cc\u200c\u0631\u0633\u062f \u0627\u062b\u0631 \u0645\u0646\u0641\u06cc \u0628\u0631 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u06a9\u0644\u06cc \u062f\u0631\u0645\u0627\u0646 \u062f\u0627\u0634\u062a\u0647 \u0628\u0627\u0634\u062f (I, C).<\/li>\n<\/ul>\n<\/li>\n<\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-d44ae3f  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<ul>\n<li>\u0627\u062f\u0627\u0645\u0647 \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 <strong>\u0645\u0647\u0627\u0631\u06a9\u0646\u0646\u062f\u0647\u200c\u0647\u0627\u06cc<\/strong><strong> VEGFR TKI <\/strong><strong>\u067e\u0633 \u0627\u0632 \u062f\u0631\u0645\u0627\u0646 \u062e\u0637 \u0627\u0648\u0644 \u0628\u0627 \u062a\u0631\u06a9\u06cc\u0628\u0627\u062a \u0647\u062f\u0641\u0645\u0646\u062f \u0639\u0644\u06cc\u0647<\/strong> <strong>PD-1<\/strong>\u060c \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f \u0645\u0631\u0627\u0642\u0628\u062a\u06cc \u0645\u062d\u0633\u0648\u0628 \u0645\u06cc\u200c\u0634\u0648\u062f \u200f[I, B].<\/li>\n<li>\u0628\u0627\u06cc\u062f \u0627\u0632 <strong>\u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0636\u062f<\/strong><strong> VEGFR<\/strong> \u06a9\u0647 \u0642\u0628\u0644\u0627\u064b \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0646\u0634\u062f\u0647\u200c\u0627\u0646\u062f \u0628\u0647\u0631\u0647 \u06af\u0631\u0641\u062a \u200f[I, B].<\/li>\n<li><strong>Cabozantinib<\/strong> \u062f\u0627\u0631\u0648\u06cc \u0627\u0631\u062c\u062d \u0628\u0631\u0627\u06cc \u062f\u0631\u0645\u0627\u0646 \u062e\u0637 \u062f\u0648\u0645 \u0627\u0633\u062a \u200f[II, B].<\/li>\n<li>\u0633\u0627\u06cc\u0631 \u06af\u0632\u06cc\u0646\u0647\u200c\u0647\u0627 \u0646\u06cc\u0632 \u0634\u0627\u0645\u0644 <strong>Axitinib<\/strong>\u060c <strong>Lenvatinib\u2013Everolimus<\/strong>\u060c <strong>Pazopanib<\/strong>\u060c <strong>Sunitinib<\/strong> \u0648 <strong>Tivozanib<\/strong> \u0647\u0633\u062a\u0646\u062f \u200f[III, B].<\/li>\n<li>\u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646\u06cc \u06a9\u0647 \u062f\u0631 \u062e\u0637 \u0627\u0648\u0644 <strong>\u062f\u0631\u0645\u0627\u0646 \u0628\u0627<\/strong><strong> TKI <\/strong><strong>\u0636\u062f<\/strong><strong> VEGFR<\/strong> \u062f\u0631\u06cc\u0627\u0641\u062a \u06a9\u0631\u062f\u0647\u200c\u0627\u0646\u062f:<\/li>\n<li><strong>Nivolumab<\/strong> (\u062f\u0631 \u0635\u0648\u0631\u062a \u062f\u0631 \u062f\u0633\u062a\u0631\u0633 \u0628\u0648\u062f\u0646 \u0648 \u0646\u0628\u0648\u062f \u06a9\u0646\u062a\u0631\u0627\u0627\u0646\u062f\u06cc\u06a9\u0627\u0633\u06cc\u0648\u0646) \u200f(I, A\u061b \u0627\u0645\u062a\u06cc\u0627\u0632 ESMO-MCBS : \u06f5) \u0648 <strong>Cabozantinib<\/strong> \u200f[I, A] \u00a0\u0647\u0631 \u062f\u0648 \u0628\u0627\u0639\u062b <strong>\u0627\u0641\u0632\u0627\u06cc\u0634 \u0628\u0642\u0627\u06cc \u06a9\u0644\u06cc<\/strong><strong> (OS)<\/strong> \u0645\u06cc\u200c\u0634\u0648\u0646\u062f.<\/li>\n<li>\u0633\u0627\u06cc\u0631 \u06af\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u0642\u0627\u0628\u0644\u200c\u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0639\u0628\u0627\u0631\u062a\u200c\u0627\u0646\u062f \u0627\u0632: <strong>Axitinib<\/strong>\u060c <strong>Everolimus<\/strong> \u0648 <strong>Lenvatinib\u2013Everolimus<\/strong> \u200f[II, B].<\/li>\n<li><strong>Belzutifan<\/strong> \u0646\u06cc\u0632 \u06af\u0632\u06cc\u0646\u0647\u200c\u06cc \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646\u06cc \u0627\u0633\u062a \u06a9\u0647 \u067e\u0633 \u0627\u0632 \u062f\u0631\u06cc\u0627\u0641\u062a <strong>\u062f\u0631\u0645\u0627\u0646 \u062a\u0631\u06a9\u06cc\u0628\u06cc \u0636\u062f<\/strong><strong> VEGFR\u2013PD-1<\/strong> \u00a0\u062f\u0686\u0627\u0631 \u067e\u06cc\u0634\u0631\u0641\u062a \u0628\u06cc\u0645\u0627\u0631\u06cc \u0634\u062f\u0647\u200c\u0627\u0646\u062f \u200f(III, B\u061b \u062f\u0627\u0631\u0627\u06cc \u062a\u0623\u06cc\u06cc\u062f\u06cc\u0647 FDA \u0648\u0644\u06cc \u0641\u0627\u0642\u062f \u062a\u0623\u06cc\u06cc\u062f\u06cc\u0647 EMA).<\/li>\n<\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f388b57 e-con-full e-flex e-con e-child\" data-id=\"f388b57\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u062a\u0631\u06a9\u06cc\u0628 Lenvatinib\u2013pembrolizumab \u200f(I, A\u061b \u0627\u0645\u062a\u06cc\u0627\u0632 ESMO-MCBS: \u06f4)\u060c Axitinib\u2013pembrolizumab \u00a0\u200f(I, A\u061b \u0627\u0645\u062a\u06cc\u0627\u0632: \u06f4) \u06cc\u0627 Cabozantinib\u2013nivolumab \u200f (I, A\u061b \u0627\u0645\u062a\u06cc\u0627\u0632: \u06f1) \u0628\u0631\u0627\u06cc \u062f\u0631\u0645\u0627\u0646 \u062e\u0637 \u0627\u0648\u0644 ccRCC \u067e\u06cc\u0634\u0631\u0641\u062a\u0647 \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c \u0635\u0631\u0641\u200c\u0646\u0638\u0631 \u0627\u0632 \u06af\u0631\u0648\u0647 \u062e\u0637\u0631 \u062f\u0631 \u0637\u0628\u0642\u0647\u200c\u0628\u0646\u062f\u06cc IMDC. \u0647\u06cc\u0686 \u062a\u0631\u06a9\u06cc\u0628 \u062a\u0631\u062c\u06cc\u062d\u06cc \u0645\u06cc\u0627\u0646 \u0645\u0647\u0627\u0631\u06a9\u0646\u0646\u062f\u0647 PD-1 \u0648 TKI\u0647\u0627\u06cc \u0636\u062f VEGFR \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0631\u062f \u0648 \u0645\u0642\u0627\u06cc\u0633\u0647\u200c\u0647\u0627\u06cc \u063a\u06cc\u0631\u0645\u0633\u062a\u0642\u06cc\u0645 \u0645\u06cc\u0627\u0646 \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u0645\u062e\u062a\u0644\u0641 \u062a\u0648\u0635\u06cc\u0647 \u0646\u0645\u06cc\u200c\u0634\u0648\u062f. \u062a\u0631\u06a9\u06cc\u0628 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2602","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/uro-med.ir\/kidney-cancer\/wp-json\/wp\/v2\/pages\/2602","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/uro-med.ir\/kidney-cancer\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/uro-med.ir\/kidney-cancer\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/uro-med.ir\/kidney-cancer\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/uro-med.ir\/kidney-cancer\/wp-json\/wp\/v2\/comments?post=2602"}],"version-history":[{"count":74,"href":"https:\/\/uro-med.ir\/kidney-cancer\/wp-json\/wp\/v2\/pages\/2602\/revisions"}],"predecessor-version":[{"id":4347,"href":"https:\/\/uro-med.ir\/kidney-cancer\/wp-json\/wp\/v2\/pages\/2602\/revisions\/4347"}],"wp:attachment":[{"href":"https:\/\/uro-med.ir\/kidney-cancer\/wp-json\/wp\/v2\/media?parent=2602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}